REAL MS: A Longitudinal Study Inside iConquerMS
Launched in 2014, REAL-MS is one of iConquerMS's longest-running research initiatives, tracking how MS changes over time directly from the people living it.
Ten years of real-world data
REAL MS participants share how MS is affecting their lives, building one of the most comprehensive longitudinal datasets in the field.
Whole-person view
Captures MS history and symptoms alongside daily life factors like activity, wellness, and comorbidities
Validated instruments
Built on standardized tools like PROMIS and PDDS, so findings hold up to research scrutiny
Built to evolve
New assessments can be added as they become valuable to the community and research partners
Supports advanced modeling
Structured to support AI, machine learning, and other analytic approaches, from disease trajectory modeling to symptom clustering and early predictors of progression.
See REAL-MS in the ACP Data Challenge PilotWhat REAL MS captures
Research partners share self-reported health data twice yearly, including:
- Demographics
- MS history: subtype, disease-modifying therapy, symptoms
- Comorbidities
- Physical activity, wellness, and diet
- PROMIS Global Health scale
- Patient Determined Disease Steps (PDDS)
- Neuro-QoL
- SymptoMScreen
REAL-MS can also incorporate new assessments as they become valuable to our community and research partners.
Ready to put REAL-MS data to work?
Whether you're designing a new study or looking to strengthen one already underway, our research team can help figure out if REAL MS is the right fit.